The main component of the coating is phosphorylcholine (PC). PC is the main lipid on the outer layer of the non-activated cell membrane, which is an amphiphilic (hydrophilic and lipophilic) phospholipid, that resists protein and cell adhesion.
PC is covalently bonded to the surface of the devices, it can reduce the thrombosis caused by protein aggregation and serves as an anti-clotting agent. Material containing PC is surrounded by water molecules, and these water molecule layers effectively cover the substrate to which it is applied, providing a biological "non-stick" surface that resists protein and cell adhesion, and acts as an anti-adhesive and anti-crystallization agent.
- Reduces clot formation
- Reduces biofilm formation and infection
- Long-lasting coating effectiveness
- Coating thickness is at the nanometer level
jMedtech has been incorporated its antithrombogenic coatings into 11 different products, showcasing a broad foundation of uses and extensive experience. The coated products have demonstrated a significant anti-coagulative effect.
- Stent grafts
- Metal implants
- Introducer sheaths
- Central Venous Catheter (CVC)
- Heart valves
- Vascular grafts
- Neurological guidewires and catheters
- Haemodialysis catheters
- Embolic protection devices
- Vena cava filters
- Peripherally Inserted Central Catheter (PICC)
- Others
We have done a series of tests on jHemo PC® Phosphorylcholine Anticoagulant Coating, the following is the result of a comparative test.
-
Uncoated stent surface - 1000x
-
PC-coated stent surface - 1000x
-
Embolism Protection Umbrella
-
No Coating
-
With Coating
-
Vascular Graft
-
No Coating
-
With Coating
-
Braided Stent
-
No Coating
-
With Coating
-
Extracorporeal Circulation Catheter
-
No Coating
-
With Coating
Download more information on how our jHemo PC® Phosphorylcholine Hemocompatible Coating and expertise can tackle unmet needs.
