jHemo PC® Phosphorylcholine Hemocompatible Coating
jHemo PC® phosphorylcholine hemocompatible coating is hydrophilic, biocompatible, and resistant to protein, cellular and microbial adhesion. Performance tests of the coating demonstrated that, compared to uncoated devices, thrombosis weight is reduced by 90% and clotting time is increased by 50%. The coatings can be used in a variety of cardiovascular and neurovascular medical devices.
Product Introduction
The main component of the coating is phosphorylcholine (PC). PC is the main lipid on the outer layer of the non-activated cell membrane, which is an amphiphilic (hydrophilic and lipophilic) phospholipid, that resists protein and cell adhesion.
PC is covalently bonded to the surface of the devices, it can reduce the thrombosis caused by protein aggregation and serves as an anti-clotting agent. Material containing PC is surrounded by water molecules, and these water molecule layers effectively cover the substrate to which it is applied, providing a biological "non-stick" surface that resists protein and cell adhesion, and acts as an anti-adhesive and anti-crystallization agent.
Coating thickness is thin
Key Features
- Reduces clot formation
- Reduces biofilm formation and infection
- Long-lasting coating effectiveness
- Coating thickness is at the nanometer level.
Performance Tests
We have done a series of tests on jHemo PC® Phosphorylcholine Anticoagulant Coating, the following is the result of a comparative test.
SEM
Uncoated stent surface - 1000x
PC-coated stent surface - 1000x
Static thrombosis test comparison
Embolism Protection Umbrella
Embolism Protection Umbrella
Before Coating
After Coating
Vascular Graft
Vascular Graft
Before Coating
After Coating
Braided Stent
Braided Stent
Before Coating
After Coating
Grafted Stent
Grafted Stent
Before Coating
After Coating
