jHemo PC® Phosphorylcholine Hemocompatible Coating
The jHemo PC® Hemocompatible Coating is formulated with the primary phospholipid head group present in the outer leaflet of the red blood cell membrane. This imparts a camouflage effect to the coated device within the body, reducing the risk of blood clot formation. The coating provides a biological "non-stick" surface to medical devices, effectively preventing adhesion of proteins and cells.
Product Introduction

The main component of the coating is phosphorylcholine (PC). PC is the main lipid on the outer layer of the non-activated cell membrane, which is an amphiphilic (hydrophilic and lipophilic) phospholipid, that resists protein and cell adhesion.

PC is covalently bonded to the surface of the devices, it can reduce the thrombosis caused by protein aggregation and serves as an anti-clotting agent. Material containing PC is surrounded by water molecules, and these water molecule layers effectively cover the substrate to which it is applied, providing a biological "non-stick" surface that resists protein and cell adhesion, and acts as an anti-adhesive and anti-crystallization agent.

Key Features
  • Reduces clot formation
  • Reduces biofilm formation and infection
  • Long-lasting coating effectiveness
  • Coating thickness is at the nanometer level
Application product

jMedtech has been incorporated its antithrombogenic coatings into 11 different products, showcasing a broad foundation of uses and extensive experience. The coated products have demonstrated a significant anti-coagulative effect.

  • Stent grafts
  • Metal implants
  • Introducer sheaths
  • Central Venous Catheter (CVC)
  • Heart valves
  • Vascular grafts
  • Neurological guidewires and catheters
  • Haemodialysis catheters
  • Embolic protection devices
  • Vena cava filters
  • Peripherally Inserted Central Catheter (PICC)
  • Others
Performance Tests

We have done a series of tests on jHemo PC® Phosphorylcholine Anticoagulant Coating, the following is the result of a comparative test.

SEM
  • Uncoated stent surface - 1000x
  • PC-coated stent surface - 1000x
Static thrombosis test comparison
  • Embolism Protection Umbrella
  • No Coating
  • With Coating
  • Vascular Graft
  • No Coating
  • With Coating
  • Braided Stent
  • No Coating
  • With Coating
  • Extracorporeal Circulation Catheter
  • No Coating
  • With Coating