jHemo PC® Phosphorylcholine Hemocompatible Coating

The jHemo PC® Hemocompatible Coating is formulated with the primary phospholipid head group present in the outer leaflet of the red blood cell membrane. This imparts a camouflage effect to the coated device within the body, reducing the risk of blood clot formation. The coating provides a biological "non-stick" surface to medical devices, effectively preventing adhesion of proteins and cells.

Product Introduction

The main component of the coating is phosphorylcholine (PC). PC is the main lipid on the outer layer of the non-activated cell membrane, which is an amphiphilic (hydrophilic and lipophilic) phospholipid, that resists protein and cell adhesion.

PC is covalently bonded to the surface of the devices, it can reduce the thrombosis caused by protein aggregation and serves as an anti-clotting agent. Material containing PC is surrounded by water molecules, and these water molecule layers effectively cover the substrate to which it is applied, providing a biological "non-stick" surface that resists protein and cell adhesion, and acts as an anti-adhesive and anti-crystallization agent.

Key Features

Reduces clot formation
Reduces biofilm formation and infection
Long-lasting coating effectiveness
Coating thickness is at the nanometer level

Application product

jMedtech has been incorporated its antithrombogenic coatings into 11 different products, showcasing a broad foundation of uses and extensive experience. The coated products have demonstrated a significant anti-coagulative effect.