Hygea® Heparin Antithrombogenic Coating

Hygea® heparin antithrombogenic coating is a chemically bonded coating for use on blood-contacting medical devices, which prevents thrombosis and reduces adhesion of blood components. It is durable, biocompatible and is suitable for stent implants, metal implants, introducer sheaths, vascular grafts, CVC, PICC, hemodialysis catheters, and other applications.

Hygea® Heparin Antithrombogenic Coating

Product Introduction

The coating is chemically bonded to the surface of devices, grafting modified heparin onto the surface of the medical devices, effectively inhibiting formation of thrombus. During long term use, the coating can still maintain its integrity and function, and will not degrade with use.

Product Advantages

Product Advantages

  • Hygea® heparin coating shows a significant anticoagulant effect, through effectively reducing protein and platelet adhesion, thus reducing thrombus formation.
  • It has good biocompatibility.
  • During long term use, the coating retains its integrity and function.
  • Coating thickness is at the nanometer level.

Applications

  • Stent grafts
  • Metal implants
  • Introducer sheaths
  • Vascular grafts
  • CVC
  • PICC
  • Haemodialysis catheters
  • Others

Performance Tests

We have done a series of experiments with heparin coating, here are the results

SEM

SEM Before coating

Uncoated PU
Uncoated PU surface, completely covered by platelets and fibrinogen

SEM After coating

PU coated with cured heparin coating
The surface of PU with cured heparin coating shows a dramatic reduction in adhesion of platelets.

Comparison of Static Thrombus Test

Grafted Stent

Graft Stent

Grafted Stent

Graft Stent Before coating

Before coating

Graft Stent After coating

After coating

ECMO-PMP

ECMO-PMP

ECMO-PMP

ECMO-PMP Before coating

Before coating

ECMO-PMP After coating

After coating

Braided Stent

Steng

Braided Stent

Steng Before coating

Before coating

Steng After coating

After coating

Vascular Graft

Vascular Grafts

Vascular Graft

Vascular Grafts Before coating

Before coating

Vascular Grafts After coating

After coating

Balloon Catheter

Balloon Catheter

Balloon Catheter

Balloon Catheter Before coating

Before coating

Balloon Catheter After coating

After coating

Central Venous Catheter

PICC

Central Venous Catheter

PICC Before coating

Before coating

PICC After coating

After coating

Extracorporeal Circulation Catheter

ECMO-PVC

Extracorporeal Circulation Catheter

ECMO-PVC Before coating

Before coating

ECMO-PVC After coating

After coating

Product Inquiry

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