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Hydrophilic Coating

Hydrophilic coatings are designed to provide medical devices such as catheters with a slippery surface, which offers comfort of catheters insertion by maintaining lubricity throughout procedure. Hydrophilic coatings reduce insertion force and allow catheters to traverse vasculature more easily. Such coatings will also avoid severe abrasion between the device surface and the tissues/vessel walls.

jMedtech owns a series of proprietary jAquaTM hydrophilic coating formula and advanced UV-curing technology. jAquaTM hydrophilic coating can be applied to a broad variety of materials, including polyurethane, polyvinyl chloride, latex, pebax, nylon, polypropylene, polyethylene, fluorinated ethylene propylene, polyimide and silicone elastomers etc.

jMedtech hydrophilic coating helps to achieve optimal performance for devices in different clinical area, such as balloon catheters and stent delivery systems in both coronary and peripheral system, central venous catheters (CVC), guidewires (including PU jacket guidewire and metal guidewire with coil) ,  intermittent urinary catheters, foley catheters, guiding sheath, guiding catheter, introducer sheath, etc. Essentially, any device needs to be navigated through tortuous and narrow anatomies can benefit from jAquaTM hydrophilic coating.


How does it work?

Hydrophilic coatings exhibit hydrophilic characteristics. The coating polymer matrix participates in dynamic hydrogen bonding with surrounding water molecules. In Hydrophilic coatings, biocompatible hydrophilic polymers are entangled with the supporting network to form a hydrogel material which helps to trap water molecules and to keep the polymer matrix hydrated. When the Hydrophilic coating is exposed to water or body fluids, the coated surface becomes wettable and hydrophilic.Hydrophilic Coating


Features and Properties

  • Lubricity - Hydrophilic coating produces low-friction surface that reduces tissue damage as well as to facilitate device delivery

  • Durability-Hydrophilic coating maintains its integrity and lubricity after above 50cycles of friction test.

  • Low particulates-Hydrophilic coating maintains lubricity and durability with low particulates releasing.

  • Flexibility-Hydrophilic coating can withstand bending or be used in torturous paths without cracking or delaminating.

  • Substrates coated - Hydrophilic coating can be applied to various plastics and metals. Polyurethane (PU), polyvinyl chloride (PVC), latex, pebax, nylon, polypropylene (PP), polyethylene (PE), fluorinated ethylene propylene (FEP), polyimide (PI) and silicone elastomers, etc.

  • Coating thickness- The coating is very thin, which will induce negligible dimensional change to substrate.

  • Biocompatibility - Coating is demonstrated to be biocompatible.

  • Sterilization - Medical devices treated with jAquaTM hydrophilic coating can be sterilized using ethylene oxide (EO) and E-beam.


Technology

The hydrophilic coating curing technology is based on UV.

For some materials, one-step coating is sufficient to achieved desired lubricity.

For most of the materials, a primer or base coating is necessary to yield a durable lubricious surface. The primer coating layer is a dense network at the substrate interface, which provides a tie-layer for the top coating layer to bond with. The top coating layer is a functional layer, which is highly hydrophilic and flexible.

The benefits of hydrophilic coating technology from jMedtech are:

  • UV curing yields polymer matrix with tuneable lubricity and durability.

  • UV activated crosslinking reduces curing time to minutes, which significantly improves manufacturing efficiency.

  • With the primer coating, the top lubricous coating is available for various substrates.

  • The coating thickness is well-controlled and tuneable for customer’s requests.

  • No harsh solvents are involved in both primer and top coatings.

  • The system works at room temperature. No harsh working condition is required.

  • Ease of integrating into manufacturing.

  • The coating is transparent before and after UV curing.


Applications

Vascular devices

  • Angioplasty catheters

  • Balloon catheters/stent delivery systems

  • Diagnostic catheters

  • Dilators

  • Guidewires

  • Intravascular sensors and catheters

  • Central Venous catheters

Non-vascular Devices

  • Intermittent catheters

  • Foley catheters

  • Urologic guidewire

  • Feeding catheters

  • Guidewire for GI endoscopy